No. Close it. Moving quickly with an open blade in your hand means that if you trip, you land with a knife in front of you and no ability to control where it goes. Closing a folder takes two seconds, and there is no task that justifies skipping them.
A fall is a reflex event. Your hands go out in front of you automatically, and whatever is in them goes too. An open blade held in that reflex arrives ahead of your body weight.
Nothing about grip strength or experience changes that reflex.
Close it, or sheathe it, or put it down and come back. If none of those is possible, walk, hold the knife with the edge turned away and pointing down and back, and watch the ground rather than your destination.
The same applies to carrying an open knife up a ladder, which is a specific and common way people get hurt.
This is one of the first rules worth passing on to anyone new to knives, alongside cutting away from yourself and never catching a dropped blade.